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Cause Frequency Physiologic gynecomastia 25 Idiopathic or unknown cause 25 Medication or substance use Table 2 10 to 25 Cirrhosis 8 Primary hypogonadism 8 5О± reductase deficiency Androgen insensitivity syndrome Congenital anorchia Hemochromatosis Klinefelter syndrome Testicular torsion Testicular trauma Viral orchitis Tumors 3 Adrenal tumors Gastric carcinoma producing hCG Large cell lung cancer producing hCG Pituitary tumors Renal cell carcinoma producing hCG Testicular tumors, particularly Leydig or Sertoli cell tumors Secondary hypogonadism 2 Kallmann syndrome Hyperthyroidism 2 Chronic renal insufficiency 1 Other 6 Familial gynecomastia Human immunodeficiency virus Malnutrition and disorders of impaired absorption e priligy review The use of albumin may cause death
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